Cloning of monkeys: the therapeutic cloned man, it's for tomorrow!

General scientific debates. Presentations of new technologies (not directly related to renewable energies or biofuels or other themes developed in other sub-sectors) forums).
izentrop
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Re: Cloning of monkeys: therapeutic cloned man, it's for tomorrow!




by izentrop » 27/01/18, 18:54

Christophe wrote:
izentrop wrote:Without going as far as cloning, there is cell therapy which makes it possible to repair damaged tissues by cultivating the patient's own cells.
but can we do it on the scale of a complete organ? The liver no doubt, the others I have more doubts ...
Still have to wait who say
newts can restore their amputated limbs using their totipotent stem cells. Even stronger: flatworms, from the group of plathelminths, are even able to devour themselves in part in case of food shortage and to regenerate all the missing parts when the food becomes more abundant ... https://www.futura-sciences.com/sante/a ... ris-38265/
For now progress is being made in mice
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Re: Cloning of monkeys: therapeutic cloned man, it's for tomorrow!




by sen-no-sen » 27/01/18, 18:57

Christophe wrote:Ah yes I see the genre: the money and the career are more important than the fusion of mother and child, pregnancy and the joy of giving life "naturally" ... My God, what a poor woman, this Peggy Sastre!


Peggy Sastre arises here as an agent of the system and typically offers us the ideology of the exponential economic system: it is up to women to adapt to the economy and not to the economy to adapt to the female gender!
It is actually easier to grow embryos in artificial uteruses than to change a few laws and adapt the labor code! : Lol:
Here we have the typical process of Exponential economism: a Faustian pact based on the complexification of solutions by saturation of problems. The planet is warming up because of GHGs, never mind! Geoengineering will save us.
A woman wants to prioritize her career, no worries, just freeze her eggs! : roll:
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Re: Cloning of monkeys: therapeutic cloned man, it's for tomorrow!




by Christophe » 07/02/18, 22:06

Waaaw ... in fact there would already be at least 1 species in nature which knows how to clone itself ... its origin may seem to be linked to humans ... A "pirate and unofficial" research or the fruit of chance by mixing species from the other side of the world together (cross out the unnecessary) ...

https://www.courrierinternational.com/a ... la-planete

A species of crayfish clones and colonizes the planet

DNA analyzes suggest that a crayfish species capable of reproducing without a male would be a genetic hybrid that appeared in the 1990s. This highly invasive species is now present in many regions of the world.


“It looks like the scenario of a bad horror film: a mutant creature with 10 legs, which reproduces asexually, escapes from its confined environment in Germany and quietly begins a global invasion, Science starts. In the space of twenty years, clones of this voracious animal spread throughout Europe and Africa, destroying ecosystems and threatening local species. "

This Z-series plot is actually the true story of Procambarus virginalis - also known as the marbled crayfish - an invasive species that first appeared in 1995 in a German aquarium. In any case, this is what the work of a team of researchers published on February 5 in Nature Ecology & Evolution suggests.

(...)

And what makes it remarkable is that not only are females capable of making clones of themselves, but also that the species “has three pairs of each chromosome instead of the usual two”, specifies Nature. According to the researchers, two of the chromosomes have almost identical gene sequences, but the third is significantly different. One of the genomes is similar to that of another crayfish, Procambarus fallax, originally from Florida and popular with aquarists.

A reaction to temperature change

“Frank Lyko hypothesizes that the marbled crayfish appeared when the genome of a male or female gamete of P. fallax was duplicated, which sometimes occurs in response to sudden changes in temperature,” continues Nature. . If these cells were then fertilized by another subject in the same aquarium, this would result in an embryo containing three copies of its genome, ”explains the researcher.

The result would then be a new species. ”


(...)
The advantages of being a clone

"Being a clone has many undeniable advantages," notes the New York Times. Marbled crayfish only give birth to fertile offspring, which allows their population to explode. ”




The hunt is on! What to solve can be the famine in certain corner of the world ... : Cheesy:
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Re: Cloning of monkeys: therapeutic cloned man, it's for tomorrow!




by Christophe » 07/02/18, 22:08

sen-no-sen wrote:A woman wants to prioritize her career, no worries, just freeze her eggs! : roll:


Yeah and after ??? To have them "put on" when you have finished "your career" or "to pay" your house at 50-55 years?

I don't really understand the logic there ...
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Re: Cloning of monkeys: therapeutic cloned man, it's for tomorrow!




by sen-no-sen » 07/02/18, 22:18

Christophe wrote:
sen-no-sen wrote:A woman wants to prioritize her career, no worries, just freeze her eggs! : roll:


Yeah and after ??? To have them "put on" when you have finished "your career" or "to pay" your house at 50-55 years?

I don't really understand the logic there ...


The logic is to be forced to wish and transform humans into economic agents.
This is evidence that the Memes of the economy become more and more in control of the situation and pushes an increasing number of individuals to alienate themselves.
Obviously egg cryogenization does not really concern low-income women ...
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Re: Cloning of monkeys: therapeutic cloned man, it's for tomorrow!




by Christophe » 07/02/18, 22:22

No "human" logic therefore ... Poor feminist task of m .... e !!!

Good stop feminists, let's talk about the crayfish! : Cheesy:
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Re: Cloning of monkeys: therapeutic cloned man, it's for tomorrow!




by Christophe » 19/02/18, 21:46

This article discusses sheep-human genetic hybridization to create organs: http://www.iflscience.com/health-and-me ... irst-time/

It will go faster than the bitching or the "ethical" debates (humanity has always seriously advanced by "playing")

In French google this gives:

For the first time, researchers have successfully produced a sheep embryo containing a small amount of human genetic code. The scientific breakthrough was announced at the meeting of the American Association for the Advancement of Science in Texas this week. This could be very important for future medical technologies because researchers hope one day to develop parts of the human body for organ donation from genetically modified animals.

“Even today, the best-fitting organs, unless they come from identical twins, don't last very long because over time the immune system continually attacks them,” said Dr. Pablo Ross of the University of California. to Davis, who is part of the group. of the team working on growing human organs in other species, in a media briefing reported by The Guardian.

To be extremely clear, the embryos were not half sheep / half humans, they were not created on a whim and without regulation, and they were all destroyed within four weeks of their creation.

The team inserted adult human stem cells into an early-stage sheep embryo, and they followed its development for 28 days. “About one in 10 cells in these sheep embryos are human,” Ross explained.

Although this ratio is tiny 0,01%, it is much higher than what scientists have been able to achieve before for pig-human chimeras. It was closer to one human cell in 100 pig cells. Sheep and pigs are used because their organs are about the right size for transplanting into humans. But to actually develop an organ, embryos should have about 000% human cells, so we're still a bit far away.

There have been ethical concerns about this threshold. Some people fear that by humanizing the cellular composition of animals, it is possible to create a pig with a human face or a sheep with a human spirit. The team has shown that they are able to focus human cells so that they can build specific organs.

"We have published several papers showing that we can target the region, so that we can avoid the differentiation of human cells into human brain or human gonads," said Dr Hiro Nakauchi of Stanford University, who is also part of of the team.

The road to potential organ donors is still an extremely long one and the challenges are not easy to overcome. For research only, the team plans to ask permission to keep the embryos longer than the current 28-day threshold, but it is by no means certain that their approach could actually lead to a viable transplant solution.

That said, it is important to continue working on it. In the United States alone, 117 people are on an organ donor waiting list and 000 people die every day waiting for a transplant.


Original article:

For the first time, researchers have been able to produce a sheep embryo that has a small amount of human genetic code. The scientific breakthrough was announced at the American Association for the Advancement of Science meeting in Texas this week. This could be very important for future medical technologies as researchers hope one day to grow human body parts for organ donation from genetically engineered animals.

“Even today the best-matched organs, except if they come from identical twins, don't last very long because with time the immune system continuously is attacking them,” said Dr Pablo Ross from the University of California, Davis, who is part of the team working towards growing human organs in other species, in a media briefing reported by the Guardian.

To be exceedingly clear, the embryos weren't half human / half sheep, they were not created on a whim and without regulation, and were all actually destroyed within four weeks of their creation.

The team inserted adult human stem cells inside an early-stage sheep embryo, and they followed its development over 28 days. “About one in 10,000 cells in these sheep embryos are human,” Ross explained.

While this ratio is a tiny 0.01 percent, it is much higher than scientists have previously been able to achieve for pig-human chimeras. That was closer to one human cell in every 100,000 pig cells. Sheep and pigs are used because their organs are roughly the right size to be transplanted into humans. But to actually develop an organ, the embryos would need to have about 1 percent of human cells, so we're still a while off.

There have been ethical concerns about this threshold. Some people worry that by humanizing the cellular composition of animals it could be possible to create a human-faced pig or a sheep with a human mind. The team has shown that they are capable of focusing the human cells to be able to construct specific organs.

“We have published several papers showing we can target the region, so we can avoid human cells differentiating into the human brain or human gonads,” Dr. Hiro Nakauchi of Stanford University, who is also part of the team.

The road to having animals as potential organ donors is still extremely long and the challenges are not easy to overcome. For research alone, the team is planning on requesting permission to keep the embryos for longer than the current threshold of 28 days, but that's not in any way a certainty that their approach could actually lead to a viable transplant solution.

That said, it's important to keep working at it. In the United States alone, 117,000 people are currently on an organ donor waiting list and 22 people die each day waiting for a transplant.


https://www.theguardian.com/science/201 ... uman-cells
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